Hypochlorous acid (HOCl) is a natural, gentle substance that your body’s own white blood cells create to fight off germs and help your skin heal from injuries, breakouts, and irritation. When used in a topical spray, it acts as a safe disinfectant that kills 99.9% of bacteria, viruses, and fungi on contact while simultaneously calming redness and supporting your skin's natural repair process. Whether you are trying to clear up acne, soothe eczema, or prepare your face for wrinkle patches, this multi-purpose mist helps keep your skin balanced and protected without the harshness of traditional alcohol or bleach.
Your Body's Natural Defense System
While it may sound like something from a chemistry lab, hypochlorous acid is actually a molecule your body knows very well. Your immune system's first line of defense, neutrophils, are white blood cells that produce it.These cells release HOCl to neutralize the threat of an invader, such as a virus or bacteria.
This natural process has been mirrored in modern skincare. Scientists are able to produce a stable form of this molecule that you can mist directly onto your face through a specialized procedure involving salt, water, and a controlled electric current. It is extremely gentle and usually doesn't cause the stinging or dryness associated with other cleaners because it is "bio-identical"—that is, it matches what your body already makes.
How It Helps Your Skin Daily
The ability of a hypochlorous acid spray to clean the skin's surface without harming the healthy cells beneath is its main advantage.
- Acne and Breakouts: HOCl targets C. acnes, the bacteria primarily responsible for acne flare-ups. It stops these microbes from multiplying without drying out your skin like benzoyl peroxide often does.
- Redness and Inflammation: It works wonders for soothing "angry" skin. It is a favorite for people with rosacea or sensitive skin because studies have shown that it can lower the signals in your body that cause swelling and itching.
- Eczema Relief: People with eczema frequently have higher levels of specific bacteria on their skin, which worsens their itching. In as little as three days, HOCl can relieve itching by balancing the environment of the skin.
- Post-Workout Refresh: Sweating can cause "maskne" or body breakouts by trapping bacteria against your skin. After working out, a quick mist can help get rid of those germs until you can take a shower.
Storage and Safety
Although hypochlorous acid works well, it is a delicate molecule. You should adhere to a few basic guidelines to maintain the best possible performance of your spray:
- Keep it in the dark: If HOCl is exposed to excessive amounts of sunlight or UV radiation, it can decompose and become simple salt water.
- Avoid heat: Instead of keeping your bottle on a sunny windowsill, store it in a cool, dark place like a cabinet.
- The "Pool" Test: Fresh HOCl smells clean and very subtle, like a swimming pool. Your spray may have expired and lost its ability to fight germs if it completely loses this scent.
Using HOCl with Facial Wrinkle Patches
Want a creative way to use hypochlorous acid spray with your other skincare products? Using wrinkle patches and a hypochlorous acid spray together is a great combo!
By forming a "occlusive" seal over the skin, wrinkle patches help retain moisture and stop the skin from folding or creasing while you sleep. Applying a patch over unclean skin, however, runs the risk of trapping oil and bacteria beneath it, which can cause breakouts.
To ensure that your skin is balanced and clean, mist your face with HOCl and let it dry before applying your wrinkle patches. By taking this easy step, you can benefit from the patch's smoothing properties without having to deal with the undesirable side effect of a morning blemish.
FAQ
Is hypochlorous acid just diluted bleach?
No. While they are related, bleach is very harsh and has a high pH that can burn the skin. Hypochlorous acid is a weak acid that is pH-balanced to be safe for even the most sensitive skin.
Can I use it with Vitamin C?
It is best to space them out. Because HOCl is an "oxidant," it can make your Vitamin C serum less effective if applied at the exact same time. Use Vitamin C in the morning and your HOCl spray in the evening.
Will it bleach my hair or clothes?
At the low concentrations used for skincare, it is very unlikely to bleach clothes or hair. However, it is always a good idea to let it dry on your skin before putting on delicate or dark-colored fabrics.
Is it safe to use around my eyes?
Yes, HOCl is actually frequently used by eye doctors to treat eyelid irritation and help clean the lash line.
Disclaimer: This information is for educational purposes only and is not medical advice. Always consult with a dermatologist before starting a new skincare regimen, especially if you have chronic skin conditions.
References
- Del Rosso, J. Q., et al. (2018). Status Report on Topical Hypochlorous Acid. J Clin Aesthet Dermatol.
- Bohn, G. A., et al. (2014). Hypochlorous Acid in Wound Cleansing and Bioburden Management.
- National Eczema Association. (2023). Hypochlorous Acid for Eczema Symptoms.
- "Periprocedural Use of HOCl Mist for Improving Healing." (2025). Journal of Cosmetic Dermatology.
If you’re looking for a hypochlorous acid spray, you can learn more about our formulation. It’s also available through select retailers, including Amazon).
Written by
Honeydew Labs Team
