If you're into skincare, you've probably heard of both hypochlorous acid (HOCl) and beta hydroxy acids (BHAs) like salicylic acid. But can you use them together? The short answer is yes—but with some caveats. Let’s break it down so you can get the most out of your skincare routine without compromising your skin barrier.

What Is Hypochlorous Acid?
Hypochlorous acid is a gentle but powerful antimicrobial agent naturally produced by white blood cells. It helps fight off bacteria, soothes inflammation, and promotes skin healing. Unlike many harsh disinfectants, HOCl is non-irritating and safe for most skin types, making it an excellent choice for sensitive or acne-prone skin.
What Is BHA?
Beta hydroxy acids (BHAs), like salicylic acid, are oil-soluble exfoliants that penetrate deep into pores to remove excess sebum and dead skin cells. This makes them particularly effective for treating acne, blackheads, and congestion.
Can You Use Them Together?
Yes, but with caution. Since BHAs exfoliate and HOCl has antimicrobial properties, they can complement each other well. However, over-exfoliating or mixing too many active ingredients can disrupt your skin barrier, leading to irritation, dryness, or increased sensitivity.
Best Practices for Using HOCl and BHA Together:
Apply Hypochlorous Acid First: HOCl can be used as a toner or mist before applying BHA to help prep and cleanse the skin.
Use BHA Sparingly: If you’re new to BHAs, start with a low concentration (0.5-2%) and gradually increase usage.
Hydration Is Key: Pair with a hydrating moisturizer to protect your skin barrier.
Sun Protection: BHAs make your skin more sensitive to the sun, so always use SPF.
Alternatives to Consider:
If you’re worried about irritation, you might want to try:
Niacinamide: A great alternative for controlling oil and soothing inflammation without exfoliation.
Azelaic Acid: Helps with acne and hyperpigmentation while being gentler on the skin.
Lactic Acid: A mild exfoliant that’s more hydrating than BHA.

Should You Try It?
If you have acne-prone or oily skin, pairing HOCl with BHA can be a game-changer. But if you have sensitive skin, it’s best to patch-test first and monitor for any signs of irritation.
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Hmm.. Can hypochlorous acid kill parasites? Learn more here.
DISCLAIMER:
This article is for informational purposes only and should not be used as a substitute for professional dermatological advice. Always consult a skincare expert before introducing new products into your routine.
References:
American Academy of Dermatology. (2023). How to safely exfoliate at home. https://www.aad.org/public/everyday-care/skin-care-secrets/routine/safely-exfoliate
Loden, M. (2018). The clinical benefits of hypochlorous acid for skincare. International Journal of Cosmetic Science, 40(5), 457-463. https://doi.org/10.1111/ics.12532
Pavicic, T., & Worge, J. (2019). Understanding the effects of beta hydroxy acids on skin. Dermatology Research and Practice, 2019, 1-10. https://doi.org/10.1155/2019/8927563
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